Getting lots of spam emails to fake users at my domain

Getting lots of spam emails to fake users at my domain

I've lately been getting hundreds of emails a day sent to fake user accounts in my organization. For example, John.Doe@mydomain.com, Jane.Doe@mydomain.com, etc. These users don't exist, but Chinese spammers are sending through tons of emails that are being caught in Quarantine. I have to go through and delete each one and it takes a very long time. Zoho customer support has not responded to me. What can I do to prevent this?

Thank you.