Problmen with nodemailer

Problmen with nodemailer

I have a problem integrating zoho with Nodemailer:
  1. let transporter = nodemailer. createTransport({
    hostname: 'smtp.zoho.com',
    secure: true,
    port: 465,
    auth: {
    pass: 'pass for app'
    }
    });
I'm getting always the same error and I try with smtp.zoho.eu too I don't know what it's happening.  
 Error: queryA EREFUSED localhost
    at QueryReqWrap.onresolve [as oncomplete] (dns.js:213:19)
  errno: 'EREFUSED',
  code: 'EDNS',
  syscall: 'queryA',
  hostname: 'smpt.zoho.com',
  command: 'CONN'