Unable to send emails from my web via smtp, gmail yes but zoho not, so how to or what happens ?

Unable to send emails from my web via smtp, gmail yes but zoho not, so how to or what happens ?

Trying to send email from my asp.net website, using zoho it never end .. wait and wait response seems smtp does not work

If I use

  'ENVIAR UN EMAIL
        Dim MM As New MailMessage
        MM.Subject = "bla bla "
        MM.From = New MailAddress(" boletin@outl.es", "boletín de subscripción")
        MM.To.Add(New System.Net.Mail.MailAddress(EmailTo, Nombre))
        MM.Body = " bla bla"
        MM.IsBodyHtml = True
        Dim SC = New SmtpClient()
        SC.Host = "smtp.zoho.com"
        SC.Port = 465
        SC.EnableSsl = True
        SC.UseDefaultCredentials = False
        SC.Credentials = New System.Net.NetworkCredential(" boletin@outl.es", "mypass")

But if I use

       SC.Host = "smtp.gmail.com"
       SC.Port = 587
       SC.Credentials = New System.Net.NetworkCredential(my gmail account and pass)
       MM.From = New MailAddress(my gmail account and pass)

then it works, 

So, How can or what is happening with soho smtp server, What I need to change ?