What is the difference in pointing MX records through domain panel and hosting panel?

What is the difference in pointing MX records through domain panel and hosting panel?

Hi,

I have used zoho for few of my clients and always pointed MX records through domain panel.
Everything works fine.

For some clients I am not authorized to change entries in domain panel. So if I use Hosting Panel {CPanel} to create Mx Entry, will it work fine or would there be any problem?

Thanks in advance for any feedbacks on this...