Does Protecting Data (i.e. selecting Data Privacy and/or Data Security) prevent creating a Lookup field into another from working?

Does Protecting Data (i.e. selecting Data Privacy and/or Data Security) prevent creating a Lookup field into another from working?

Does Protecting Data (i.e. selecting Data Privacy and/or Data Security) prevent creating a Lookup field into another from working?

I have searched everywhere for this answer and can't seem to locate it. 

Thanks,
Paul