No Admin Access

I am the creator and administrator of our ZOHO program. I have logged in as admin many times before with no problems, the latest being last week. When I tried logging in as admin today, I received an error message stating, I was not allowed to access from this machine. What's up with that? This is the machine I have always accessed it with. Does anyone know what would have changed and why I can't access it now to make changes? Thanks for any assistance.