15 minutes I cannot send e-mails from my Zoho Webmail account, I get the following message

15 minutes I cannot send e-mails from my Zoho Webmail account, I get the following message

For the last 15 minutes I cannot send e-mails from my Zoho Webmail account, I get the following message : 

Unable to connect SMTP server:smtpout.mail.zoho.com Reason:connect timed out

Please solve this as soon as possible.

Kind regards

Rupert