About smtp.zoho.com

Hello there..i have been using zoho smtp service almost 2 year,
and at november of 2017 it seems got problem for sending and receiving mail.
we have checked ping , tracert/trace route. seems all network are can't access to smtp.zoho.com.
we have double confirmed from our isp it was not blocking our access to zoho.
we have double confirmed our firewall are not blocking our access to zoho too.
wish to get some help here.
we are using SSL port 465
our server domain and ip are :
cosmicvpnpro.com
128.199.170.114