Blocked Domain - what is the sence ?

Blocked Domain - what is the sence ?

at first:sorry for my bad english

my problem: every day i receive a lot of spam - maybe 4 per hour.
I tried to block only the domain from the spam-bots - but it make not sence, i tried it with a own domain and it doesn´t work.
(in example: 1234567@abc.com - i block only abc.com as domain. but i receive emails from abc.com)
(block from the  full adress " 1234567@abc.com" make not sence by spam bots, i think that is clear)
important: block means REALLY BLOCK - not move in the spam folder
if i block a domain in hotmaol.com or gmx.net its works fine

thanks for answers