I made some tests:
It works perfectly with Firefox, Chrome or Opera, even with an old version of IE (6 I think)
With Internet Explorer 10, I can access to Zoho Invoice, Project, Writer or Creator but not CRM
Same problem with 3 different computers
Unfortunately I must use Internet Explorer
Do you have a problem of compatibility or security with IE, or is there a specific security parameter to set ?
If a compatibility problem, can you fix it ?