Can't reply or forward using pop/smtp client

Can't reply or forward using pop/smtp client

I have set up Zoho to use POP/SMTP on my email client (Pegasus Mail). Sending and receiving is working fine. However, when I try to reply or forward an email, I get an error message that says I don't have an SMTP profile set up. The profile is set up and is working fine for sending and receiving. My guess is that when I try to reply or forward email, the request is being refused by the server. Any ideas to solve this?