Can Zoho Campaign be Set-up for Cold Email Campaigns?

Can Zoho Campaign be Set-up for Cold Email Campaigns?

I have used cold email campaign tools (WoodPecker & QuickMail) prior to subscribing to ZOHO One (ZOHO Campaigns). Using ZOHO Campaigns  I want to set up a 5 email sequence and as my contacts "REPLY" to my emails I would like them to not receive any more emails in the ZOHO Campaign sequence.  I see in the AutoResponder portion of Campaigns the options to change the flow of emails is based on OPEN, CLICK, CLICK SPECIFIC LINK and UNOPENED.  What choice/setting would I select to discontinue sending emails to contacts that have REPLIED to an email in the autoresponder sequence?