Can't send mail Reason:554 5.1.8 Email Outgoing Blocked.

Can't send mail Reason:554 5.1.8 Email Outgoing Blocked.

I send messages to my clients for my agency to my targeted clients last night I got (Unable to send message;Reason:554 5.1.8 Email Outgoing Blocked) this warning.
Now I can't send mails.
Please fix this issue.