CTI click to dial through hosted IP

CTI click to dial through hosted IP

Hi, i really like the like and feel of Zoho but it's important to me to be able to do click to dial from the crm.
Is it possible to have CTI with a hosted IP telecom setup?

I understand you can use PhoneBridge but only with a physical PBX system which is old news now considering more and more businesses are using Hosted IP

any information would be really helpful

Thanks

Antony