E-mail Problem: ResponseCode 421, 4.7.1 Intrusion prevention active for

E-mail Problem: ResponseCode 421, 4.7.1 Intrusion prevention active for

Dear all,

My partner is receiving a separate e-mail from Zoho each time he sends an e-mail.  The e-mail is as follows: 

From : mailer-daemon@mail.zoho.com<mailer-daemon@mail.zoho.com>
To : 
Date : 
Subject : Mail Delivery Status Notification (Delay)
============ Forwarded message ============
This message was created automatically by mail delivery system. 

THIS IS A WARNING MESSAGE ONLY. 

YOU DO NOT NEED TO RESEND YOUR MESSAGE. 

The original message was received at Thu, 19 Oct 2017 03:07:55 -0700 
from xxx 

----- The following addresses had fatal errors -----  
[Status: Error, Address: < xxx>, ResponseCode 421, 4.7.1 Intrusion prevention active for [xxx][D]] 

Message will be retried for 4 more day(s) 

----- Transcript of session follows -----  

Received:from mail.zoho.com by mx.zohomail.com 
    with SMTP id 1508404964118877.4212590600275; Thu, 19 Oct 2017 02:22:44 -0700 (PDT) 
Message-ID:<xxxx> 
Date:Thu, 19 Oct 2017 12:22:44 +0300 
From:xxx> 
User-Agent:Zoho Mail 
To:xxx 
Subject:xxx
Content-Type:xxx
______________

Any ideas how to fix this?

Thanks!