Getting message "Mail delivery status notification(delay)

Getting message "Mail delivery status notification(delay)

Getting this a lot. I can send to the email addresses from mail other than Zoho. Searching suggests this has happened before.

Need to send emails urgently - is there a solution for this?

 ----- The following addresses had fatal errors -----
 [Status: Error, Address: <xxxx@virgin.net>, ResponseCode 421, 4.7.0 Temporarily Deferred]