Help me!!! I keep receiving this message all the time since yesterday, when i sent out email to client. The prospective receiver can't receive it.

How to fix it,plssss recommend

This message was created automatically by mail delivery system.

THIS IS A WARNING MESSAGE ONLY.

YOU DO NOT NEED TO RESEND YOUR MESSAGE.

The original message was received at Thu, 20 Aug 2015 23:24:07 -0700  from xxxx@sahasith.co.th [xxxx@sahasith.co.th]

    ----- The following addresses had fatal errors -----   

   [Status: Error, Address: <yyyy@dutchmill.co.th>, ResponseCode 421, , Host not reachable.]

Message will be retried for 4 more day(s)

    ----- Transcript of session follows -----   

 Received:from xxxx(183.88.37.161 [183.88.37.161]) by mx.zohomail.com

               with SMTPS id 1440135520888893.6254245400394; Thu, 20 Aug 2015 22:38:40 -0700 (PDT)  Message-ID:<00c701d0dbd3$a5934960$f0b9dc20$@sahasith.co.th>

 Date:Fri, 21 Aug 2015 12:38:40 +0700

 From:"pppp" <xxxx@sahasith.co.th>

 To:"yyyyl" <yyyy@dutchmill.co.th>

 Subject:RE: Re Sucrose Fatty Acid Ester  Content-Type:multipart/related;

               boundary="----=_NextPart_000_00C8_01D0DC0E.51F94D50"