Mail can't connect to account

Mail can't connect to account

Hi Zoho,
When I try to send and receive in my desktop client (Mail), I get an error by outgoing mail saying 'Mail can't connect to the account "smtp.zoho.com:myemailaddress.com". The dialog asks me to enter my password, which doesn't seem to affect anything, the error keeps coming.

I seem to be able to receive mail OK, just cannot send. I've seen on previous discussions in here this seems to be a problem with something your end?

Best,
Ngaire