our company emails being labeled as spam on recievers end

our company emails being labeled as spam on recievers end

We send emails to this company on a daily, hourly basis. Suddenly, our zoho mail has SPAM added to the subject line nd is going into thier spam folder? 

This is costing us time and money. How do I fix this other than the obvious "Add us to your safe contatc list, which we are already on.

Any thoughts