Outlook cannot connect to your outgoing (SMTP) e-mail server

Outlook cannot connect to your outgoing (SMTP) e-mail server

Just started at around 1:00 PM NY time:
Task ' info@harmonyremoterepair.com - Sending' reported error (0x80042109) : 'Outlook cannot connect to your outgoing (SMTP) e-mail server. If you continue to receive this message, contact your server administrator or Internet service provider (ISP).'