Reason: 554 5.1.8 Sender address blocked

Reason: 554 5.1.8 Sender address blocked

Hello: For two days, several of our mail accounts with zoho, can not send to certain recipients mail and the following message appears:Could not send message; Reason: 554 5.1.8 Sender address blocked

 
We have written several times and referred us to the area of ​​abuse of blocking filters, but we have not obtained any response or solution.It is a sender block problem, not the size of the mail or the number of recipients. We need urgent help. We are several
users of our blocked, we try to find the problem, but its really difficult, we cannot unblock from here
we need help urgently please.
thanks