ResponseCode 421, Host not reachable

Today i can't send email. Plz help me

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The original message was received at Sun, 30 Oct 2016 22:07:39 -0700
from Dung.nguyen@rfrevietnam.com [ Dung.nguyen@rfrevietnam.com ]

----- The following addresses had fatal errors -----
[Status: Error, Address: < khanhphan@saigonparagon.com >, ResponseCode 421, Host not reachable., Status: Error, Address: < huonghoang@saigonparagon.com >, ResponseCode 421, Host not reachable., Status: Error, Address: < phiphi@khaisilkcorp.com >, ResponseCode 421, Host not reachable., Status: Error, Address: < hienle@saigonparagon.com >, ResponseCode 421, Host not reachable., Status: Error, Address: < binhtran@saigonparagon.com >, ResponseCode 421, Host not reachable.]

Message will be retried for 4 more day(s)

----- Transcript of session follows -----

Received:from KenKomedian (27.74.240.175 [27.74.240.175]) by mx.zohomail.com
    with SMTPS id 147788766141018.700692223282886; Sun, 30 Oct 2016 21:21:01 -0700 (PDT)
Message-ID:<005001d2332e$4f908830$eeb19890$@rfrevietnam.com>
Date:Mon, 31 Oct 2016 11:21:48 +0700
From:"Dung.nguyen" < Dung.nguyen@rfrevietnam.com >
To:"'Hoang Phi Phi'" < phiphi@khaisilkcorp.com >,
    < tanakorn.pornprayuth@astonmartin-bangkok.com >,
    < lethibichhien10@gmail.com >
Cc:< khanhphan@saigonparagon.com >,
    < binhtran@saigonparagon.com >,
    "'Huong Hoang'" < huonghoang@saigonparagon.com >,
    "'Le Thi Bich Hien'" < hienle@saigonparagon.com >
Subject:RE: : Mặt bằng cho Aston martin Bangkok
Content-Type:multipart/alternative;
    boundary="----=_NextPart_000_0051_01D23368.FBF50580"