SMTP Timeout

SMTP Timeout

I am getting a timeout using three different apps when trying to send email via SMTP. Everything was working fine yesterday. Example from sSMTP:

Dec 24 16:05:39 server1 sSMTP[1788]: Unable to connect to "smtp.zoho.com" port 587.
Dec 24 16:05:39 server1 sSMTP[1788]: Cannot open smtp.zoho.com:587


Not much info, I know. 

Is this part of the upgrades?