The response from the remote server was: 550 5.7.1 Relaying denied

The response from the remote server was: 550 5.7.1 Relaying denied

Hi there. When someone tries to send me an e-mail to @eusouagil.com.br they got this message.

I don't know what's wrong. I use MAILGUN and ZOHO in same server. How do I manage that?