Why do I got "Unable to send message;Reason:554 5.1.8 Sender Address Blocked"

Why do I got "Unable to send message;Reason:554 5.1.8 Sender Address Blocked"

mandymajesticnews@zoho.com is a new account for me.  Everytime I try to send my clients an email I got the "Unable to send message;Reason:554 5.1.8 Sender Address Blocked" message.

Why is this? 

Please unblock my account.

Mandy