Email Opt Out Syncing With Zcampaigns Mailing Lists

Email Opt Out Syncing With Zcampaigns Mailing Lists

If a lead's "Email Opt Out" field is manually updated in CRM does it automatically tell your mailing list in Zcampaigns to exclude the contact from a future scheduled campaigns? or do you have to wait for the Mailing Sync to occur to catch any updates?