I believe I have seen similar requests, however, I don't believe that there has been an affirmative answer.

When I get an email from the Desk as an Agent and I reply to the user from my Outlook email client, the ticket is not automatically assigned to me. 

If I answer from within the Desk app -- it will auto-assign the ticket to me.

Is there a workflow option or a direct assignment option that will assign me an unassigned ticket simply because I replied to it from my Outlook account?

Thanks.

William