How to update zoho CRM Variables?

How to update zoho CRM Variables?

I am working on Zoho CRM extension. I can get the CRM variables value with this 

  1. ZOHO.CRM.API.getOrgVariable("variableNamespace").then(function(data){
    	console.log(data);
    });
But I want to update this CRM Variables value from the widget and how I will do that.