ResponseCode 421, Host not reachable

ResponseCode 421, Host not reachable

Team,

Could you help me resolve the below email bounced back issue. we are using Zoho Mail and some important emails are getting bounced.


Thanks,

Fernando

-------------------------------- -------------------------------- -------------------------------- --------------------------------
This message was created automatically by mail delivery system. 

THIS IS A WARNING MESSAGE ONLY. 

YOU DO NOT NEED TO RESEND YOUR MESSAGE. 

The original message was received at Tue, 29 Jan 2019 04:24:36 -0800 
from  contato@mariamuza.com.br  [ contato@mariamuza.com.br ]  

----- The following addresses had fatal errors -----  
[Status: Error, Address: < user@example.com >, ResponseCode 421, Host not reachable.] 

Message will be retried for 4 more day(s) 

----- Transcript of session follows -----  

Received:from mariamuza.com.br (ec2-18-204-107-214.compute-1.amazonaws.com [18.204.107.214]) by mx.zohomail.com 
    with SMTPS id 1548761950971808.7174514698846; Tue, 29 Jan 2019 03:39:10 -0800 (PST) 
Message-ID:<c24204f20dafc6fb0692a6b377ce3440@mariamuza.com.br> 
Date:Tue, 29 Jan 2019 11:39:09 +0000 
From:Maria Muza < contato@mariamuza.com.br > 
To: user@example.com  
Subject:Backup feito: Maria Muza - Fotografia Newborn (UpdraftPlus 1.16.5) 2019-01-29 09:39 
Content-Type:text/plain; charset=UTF-8