Hello, 

As a Zoho Desk user, Some of my customers have requested to have their profiles closed or deactivated.  Even tho deactivating a user profile is possible, within my company I do not delete user profiles because of ticket logging and also for tracking purposes later on.   

You can manually add a field so your agents on the team know that the users profile is "closed".   

Just go to Settings > Fields & Layouts > Select the department in question > Add a custom field & name is "Profile Status" > Add your options you wish to have "open", "closed", "on hold", ect > click save layout. 

Once this is done, You can now change the options on your customer profiles within Desk to best suit your needs. 

This is helpful to me and I hope some of you take advantage of this and hope it helps your business!