Sender domain reputation matters a great deal in successful inbox placement. If Gmail shows the warning “Lots of messages from yourdomain.com were identified as spam in the past,” it means recipients have been reporting your mail as spam and Gmail no longer trusts your domain — the fix is to lower your spam-complaint rate, authenticate your domain, and send only to people who want your email. Numerous factors like email subject and content, sender domain reputation, and mailing list quality play a vital role in building up domain reputation. ESPs and ISPs measure reputation for every sender domain, based on their sending practices. The domain reputation decreases whenever the email sending practice does not meet the required standard. When the reputation falls below a stipulated threshold, your sender domain may get blacklisted.
Why Gmail says your sender domain is spam – An infographic.